The HMBS Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to HMBS, hydroxymethylbilane synthase, PBGD, Porphobilinogen deaminase, and UPS. This antibody recognizes Human, Mouse, and Rat antigen. The HMBS Polyclonal Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]